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ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection

Abstract Viral myocarditis, an inflammatory disease of the heart, causes significant morbidity and mortality. Type I interferon (IFN)-mediated antiviral responses protect against myocarditis, but the mechanisms are poorly understood. We previously identified A Disintegrin And Metalloproteinase domai...

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Principais autores: Lindsey E. Bazzone, Junji Zhu, Michael King, GuanQun Liu, Zhiru Guo, Christopher R. MacKay, Pyae P. Kyawe, Natasha Qaisar, Joselyn Rojas-Quintero, Caroline A. Owen, Abraham L. Brass, William McDougall, Christina E. Baer, Timothy Cashman, Chinmay M. Trivedi, Michaela U. Gack, Robert W. Finberg, Evelyn A. Kurt-Jones
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2024-05-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-024-48524-6
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