Roxadustat attenuates heat stress-induced apoptosis and senescence in renal tubular epithelial cells by upregulating HIF-1α

Objective To investigate the effect and underlying mechanism of roxadustat on apoptosis and senescence of renal tubular epithelial cell line HK-2 induced by heat stress. Methods After HK-2 cells were treated with different concentrations of roxadustat (10, 20, 30, 40 and 50 μmol/L) for 24 h, CCK-8 a...

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Autors principals:	SONG Yongwei, WANG Ling, CHEN Wenting
Format:	Artigo
Idioma:	Chinês
Publicat:	Editorial Office of Journal of Army Medical University 2024-05-01
Col·lecció:	陆军军医大学学报
Matèries:	heat stress roxadustat hif-1α apoptosis senescence
Accés en línia:	http://aammt.tmmu.edu.cn/html/202312123.htm
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