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Glycogen Synthase Kinase 3 β Hepatocyte Deletion Attenuates Ferroptosis and Metabolic Dysfunction-associated Steatohepatitis in MiceSummaryWhat You Need to Know

Background & Aims: Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by toxic lipid-induced cellular stress (lipotoxicity), which culminates in lethal and sublethal hepatocyte injury and a sterile fibroinflammatory response. We previously reported that pharmacological inhi...

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Autori principali: Khaled Warasnhe, Akitoshi Sano, Qianqian Guo, Nantawat Satthawiwat, Xin Dai, Peyton A. Classon, Chady Meroueh, Hyun Se Kim Lee, Lucía Valenzuela-Pérez, Stella Victorelli, Adebowale O. Bamidele, Petra Hirsova, Davide Povero, Samar H. Ibrahim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2026-01-01
Serie:Cellular and Molecular Gastroenterology and Hepatology
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2352345X25001742
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