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Scaffold-enabled high-resolution cryo-EM structure determination of RNA

Abstract Cryo-EM structure determination of protein-free RNAs has remained difficult with most attempts yielding low to moderate resolution and lacking nucleotide-level detail. These difficulties are compounded for small RNAs as cryo-EM is inherently more difficult for lower molecular weight macromo...

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Autores principales: Daniel B. Haack, Boris Rudolfs, Shouhong Jin, Alexandra Khitun, Kevin M. Weeks, Navtej Toor
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2025-01-01
Colección:Nature Communications
Acceso en línea:https://doi.org/10.1038/s41467-024-55699-5
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