Sensitive, flexible, and affordable serum RNA sequencing for pathogen detection on the Oxford Nanopore platform

Abstract Metagenomic sequencing for pathogen detection has traditionally suffered from low sensitivity due to the overwhelming presence of host nucleic acids. Commercial host-depletion kits are often prohibitively expensive and limited to specific species, hindering adoption in resource-limited sett...

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Bibliografische gegevens

Hoofdauteurs:	Philippe Selhorst, Emilie Van Vyve, Francesca Falconi-Agapito, Joachim Mariën, Kevin K. Ariën
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2026-02-01
Reeks:	BMC Genomics
Onderwerpen:	SISPA CRISPR/Cas-9 Metagenomics DASH Sequencing mNGS
Online toegang:	https://doi.org/10.1186/s12864-025-12268-4
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