DNA methylation of leptin before and after weight loss intervention program among sample of Egyptian obese females: Epigenetic approach in obesity

Background/aim Obesity phenotype results from interactions between epigenotype and genotype. DNA methylation constitutes the most relevant epigenetic mechanism that regulates gene expression in human cells. Leptin (LEP) has a promoter region that presents CpG (CG dinucleotide repeats) islands which...

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Autori principali:	Nayera E. Hassan, Sahar A. El-Masry, Waheba A. Zarouk, Nayra S. Mehanna, Rehab M. Mosaad, Maha M Kobesiy, Mohamed S. Kishta, Mohamed Selim, Mahmoud A.S. Afify, Khadija Alian, Aya Khalil, Heba T. Aboud
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wolters Kluwer Medknow Publications 2024-12-01
Serie:	Journal of the Arab Society for Medical Research
Soggetti:	diet intervention leptin levels leptin promoter methylation obesity
Accesso online:	https://journals.lww.com/10.4103/jasmr.jasmr_8_24
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