The Connected Steady State Model and the Interdependence of the CSF Proteome and CSF Flow Characteristics

Here we show that the hydrodynamic radii-dependent entry of blood proteins into cerebrospinal fluid (CSF) can best be modeled with a diffusional system of consecutive interdependent steady states between barrier-restricted molecular flux and bulk flow of CSF. The connected steady state model fits pr...

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Hlavní autoři:	Fabian Metzger, Daniel Mischek, Frédéric Stoffers
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2017-05-01
Edice:	Frontiers in Neuroscience
Témata:	cerebrospinal fluid steady state blood-brain barrier blood-cerebrospinal fluid barrier neuroimmunology rostrocaudal gradient
On-line přístup:	http://journal.frontiersin.org/article/10.3389/fnins.2017.00241/full
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