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Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A

Serotonin (5-HT) is one of the key bioamines of nonalcoholic fatty liver disease (NAFLD). Its mechanism of action in autonomic neural signal pathways remains unexplained; hence, we evaluated the involvement of 5-HT and related signaling pathways via autonomic nerves in NAFLD. Diet-induced NAFLD anim...

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Hoofdauteurs: Takashi Owaki, Kenya Kamimura, Masayoshi Ko, Itsuo Nagayama, Takuro Nagoya, Osamu Shibata, Chiyumi Oda, Shinichi Morita, Atsushi Kimura, Takeki Sato, Toru Setsu, Akira Sakamaki, Hiroteru Kamimura, Takeshi Yokoo, Shuji Terai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2022-07-01
Reeks:Disease Models & Mechanisms
Onderwerpen:
fatty liver
autonomic neuron
5-ht
antagonist
brain
Online toegang:http://dmm.biologists.org/content/15/7/dmm049612
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