Role of Store-Operated Ca²⁺ Entry in the Pulmonary Vascular Remodeling Occurring in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a severe and multifactorial disease. PAH pathogenesis mostly involves pulmonary arterial endothelial and pulmonary arterial smooth muscle cell (PASMC) dysfunction, leading to alterations in pulmonary arterial tone and distal pulmonary vessel obstruction and r...

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Autori principali:	Bastien Masson, David Montani, Marc Humbert, Véronique Capuano, Fabrice Antigny
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-11-01
Serie:	Biomolecules
Soggetti:	PAH Ca<sup>2+</sup> signaling Orai STIM TRPC IP<sub>3</sub>R
Accesso online:	https://www.mdpi.com/2218-273X/11/12/1781
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