QR code

Early hypersynchrony in juvenile PINK1-/- motor cortex is rescued by antidromic stimulation

In Parkinson’s disease, cortical networks show enhanced synchronized activity but whether this precedes motor signs is unknown. We investigated this question in PINK1-/- mice, a genetic rodent model of the PARK6 variant of familial Parkinson’s disease which shows impaired spontaneous locomotion at 1...

Volledige beschrijving

Bewaard in:
Hoofdauteurs: Romain eCARRON, Anton eFilipchuk, Romain eNardou, abhinav eSINGH, francois J MICHEL, Mark D Humphries, Constance eHammond
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2014-05-01
Reeks:Frontiers in Systems Neuroscience
Onderwerpen:
synchronization
cortical network
deep brain stimulation (DBS)
familial Parkinson
antidromic activation
Online toegang:http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00095/full
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items