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Association between statin use, the vaginal microbiome, and Gardnerella vaginalis vaginolysin-mediated cytotoxicity.

BACKGROUND:Bacterial vaginosis (BV) is the leading dysbiosis of the vaginal microbiome. The pathways leading towards the development of BV are not well understood. Gardnerella vaginalis is frequently associated with BV. G. vaginalis produces the cholesterol-dependent cytolysin (CDC), vaginolysin, wh...

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Hlavní autoři: Abdallah A Abdelmaksoud, Philippe H Girerd, Erin M Garcia, J Paul Brooks, Lauren M Leftwich, Nihar U Sheth, Steven P Bradley, Myrna G Serrano, Jennifer M Fettweis, Bernice Huang, Jerome F Strauss, Gregory A Buck, Kimberly K Jefferson
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2017-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC5573284?pdf=render
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