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Evaluation of Cholera Toxin B Subunit as a Novel Carrier Protein for Polysaccharide Conjugate Vaccines

<b>Background:</b> The immunogenicity of polysaccharide conjugate vaccines is critically influenced by the choice of carrier protein, which promotes a T-cell-dependent immune response mechanism leading to strong antibody production. In this study, the cholera toxin B subunit (CTB), a non-toxic penta...

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Principais autores: Chathuranga Siriwardhana, Aakriti Bajracharya, Florence Seal, Anup Datta, Subhash Kapre
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-11-01
coleção:Vaccines
Assuntos:
cholera toxin B subunit (CTB)
polysaccharide–protein conjugates
carrier protein
CDAP conjugation
immunogenicity
Acesso em linha:https://www.mdpi.com/2076-393X/13/11/1159
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