Dissecting the Role of SMYD2 and Its Inhibitor (LLY-507) in the Treatment of Chemically Induced Non-Small Cell Lung Cancer (NSCLC) by Using Fe₃O₄ Nanoparticles Drug Delivery System

Cancer therapies based on nanoparticles with a loaded drug can overcome the problem of the drug’s toxic effects in the traditional chemotherapeutic approach. In this study, we loaded LLY-507, a potent inhibitor of SMYD2, a methyltransferase enzyme, on iron oxide nanoparticles (IONPs). The prepared n...

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Bibliografiska uppgifter

Huvudupphov:	Aasma Munawwar, Amna Sajjad, Azhar Rasul, Mehran Sattar, Farhat Jabeen
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2023-07-01
Serie:	Pharmaceuticals
Ämnen:	SMYD2 LLY-507 IONPs adenocarcinoma NSCLC
Länkar:	https://www.mdpi.com/1424-8247/16/7/986
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