Guanidinylated Polymyxins as Outer Membrane Permeabilizers Capable of Potentiating Rifampicin, Erythromycin, Ceftazidime and Aztreonam against Gram-Negative Bacteria

Polymyxins are considered a last-line treatment against infections caused by multidrug-resistant (MDR) Gram-negative bacteria. In addition to their use as a potent antibiotic, polymyxins have also been utilized as outer membrane (OM) permeabilizers, capable of augmenting the activity of a partner an...

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Автори:	Danzel Marie Ramirez, Danyel Ramirez, Gilbert Arthur, George Zhanel, Frank Schweizer
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2022-09-01
Серія:	Antibiotics
Предмети:	outer membrane permeabilizer antibiotic potentiator antibiotic adjuvant polymyxins <i>Pseudomonas aeruginosa</i> <i>Acinetobacter baumannii</i>
Онлайн доступ:	https://www.mdpi.com/2079-6382/11/10/1277
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