Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis

Summary: Immunotherapy has revolutionized cancer treatment, yet challenges persist, such as resistance and lethal thromboembolism, necessitating dual-purpose strategies. Targeting ferroptosis emerges as a promising strategy to enhance immunotherapy efficacy, prompting our investigation of antiplatel...

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Autori principali:	Qian Zhou, Yuming Sun, Songtao Du, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Yu Meng, Yixiao Xiong, Zhili Deng, Xinwei Kuang, Xiaowei Liang, Hong Liu, Guangtong Deng, Xiang Chen, Furong Zeng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-10-01
Serie:	Cell Reports Medicine
Soggetti:	vorapaxar ferroptosis immunotherapy FOXO1 HMOX1
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2666379125004446
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