Prevention of postoperative proliferative vitreoretinopathy in complex retinal detachments with serial intravitreal methotrexate injections

Abstract Background Proliferative vitreoretinopathy (PVR) remains the leading cause of surgical failure after rhegmatogenous retinal detachment (RRD) repair. Intravitreal methotrexate (MTX) has emerged as a potential antiproliferative adjunct; however, the available evidence remains inconclusive. Th...

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Detalhes bibliográficos

Principais autores:	Lucas Valadão de Brito Soares, Tiago Nelson de Oliveira Rassi, Wener Passarinho Cella, Mauricio Maia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	International Journal of Retina and Vitreous
Assuntos:	Proliferative vitreoretinopathy Rhegmatogenous retinal detachment Intravitreal methotrexate Pars plana vitrectomy Retinal reattachment Retinectomy
Acesso em linha:	https://doi.org/10.1186/s40942-026-00856-9
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