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Treating Metastatic Brain Cancers With Stem Cells

Stem cell therapy may present an effective treatment for metastatic brain cancer and glioblastoma. Here we posit the critical role of a leaky blood-brain barrier (BBB) as a key element for the development of brain metastases, specifically melanoma. By reviewing the immunological and inflammatory res...

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Autores principales: Nadia Sadanandan, Alex Shear, Beverly Brooks, Madeline Saft, Dorothy Anne Galang Cabantan, Chase Kingsbury, Henry Zhang, Stefan Anthony, Zhen-Jie Wang, Felipe Esparza Salazar, Alma R. Lezama Toledo, Germán Rivera Monroy, Joaquin Vega Gonzales-Portillo, Alexa Moscatello, Jea-Young Lee, Cesario V. Borlongan
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021-11-01
Colección:Frontiers in Molecular Neuroscience
Materias:
blood brain barrier
melanoma
brain metastases
stem cell therapy
bone marrow derived mesenchymal stem cell
endothelial progenitor cell
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fnmol.2021.749716/full
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