Sensory neuron cultures derived from adult db/db mice as a simplified model to study type-2 diabetes-associated axonal regeneration defects

Diabetic neuropathy (DN) is an early common complication of diabetes mellitus (DM), leading to chronic pain, sensory loss and muscle atrophy. Owing to its multifactorial etiology, neuron in vitro cultures have been proposed as simplified systems for DN studies. However, the most used models currentl...

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Автори:	Cristian De Gregorio, Fernando Ezquer
Формат:	Artigo
Мова:	Inglês
Опубліковано:	The Company of Biologists 2021-01-01
Серія:	Disease Models & Mechanisms
Предмети:	type-2 diabetes mellitus diabetic neuropathy adult sensory neuron cultures neuritic regeneration dorsal root ganglia
Онлайн доступ:	http://dmm.biologists.org/content/14/1/dmm046334
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