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Regulatory dissection of the severe COVID-19 risk locus introgressed by Neanderthals

Individuals infected with the SARS-CoV-2 virus present with a wide variety of symptoms ranging from asymptomatic to severe and even lethal outcomes. Past research has revealed a genetic haplotype on chromosome 3 that entered the human population via introgression from Neanderthals as the strongest g...

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Principais autores: Evelyn Jagoda, Davide Marnetto, Gayani Senevirathne, Victoria Gonzalez, Kaushal Baid, Francesco Montinaro, Daniel Richard, Darryl Falzarano, Emmanuelle V LeBlanc, Che C Colpitts, Arinjay Banerjee, Luca Pagani, Terence D Capellini
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2023-02-01
coleção:eLife
Assuntos:
MPRA
COVID-19
Neandertal introgression
cis-regulation
CCR1
CCR5
Acesso em linha:https://elifesciences.org/articles/71235
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