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Marginal Contribution of Pathogenic RAD51D Germline Variants to Pakistani Early-Onset and Familial Breast/Ovarian Cancer Patients

Introduction: RAD51D has been reported as a breast cancer (BC) and ovarian cancer (OC) predisposition gene, particularly among Caucasian populations. We studied the prevalence of RAD51D variants in Pakistani BC/OC patients. Materials and methods: In total, 371 young or familial BC/OC patients were...

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Autori principali: Noor Muhammad, Muhammad Sohail Afzal, Ute Hamann, Muhammad Usman Rashid
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shaukat Khanum Memorial Trust 2024-06-01
Serie:Journal of Cancer and Allied Specialties
Soggetti:
Breast cancer
germline variants
ovarian cancer
Pakistan
RAD51D
Accesso online:https://journals.sfu.ca/jcas/index.php/jcas/article/view/617
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