Less locus coeruleus degeneration and its enhanced influence on neural circuit in Parkinson's tremor

Objectives: The involvement of the locus coeruleus in Parkinson's tremor remains unclear. We aimed to decode the role of locus coeruleus in Parkinson's tremor. Methods: We used MRI to examine 120 Parkinson's disease, including 48 tremor-dominant (TD) and 72 postural instability/gait disorder (PIGD),...

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Detalhes bibliográficos

Principais autores:	Junyan Sun, Lili Chen, Liang Li, Tao Wu, Tao Feng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-09-01
coleção:	Neurobiology of Disease
Assuntos:	Locus coeruleus Tremor Cerebello-thalamo-cortical circuit Contrast-to-noise ratio Effective connectivity
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996125001767
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