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Metabolic-pathway-based classification of tendinopathy reveals a precise therapeutic strategy targeting chondro-modulatory tenocytes

Abstract Tendinopathy is a prevalent degenerative condition driven by complex metabolic dysregulation, yet its inherent metabolic heterogeneity remains poorly characterized, hindering targeted therapeutic development. To address this, we performed systematic multi-omics profiling of human rotator cu...

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Autori principali: Junchao Luo, Zetao Wang, Ruifu Lin, Jiayun Huang, Chenqi Tang, Honglu Cai, Yang Fei, Dengfeng Ruan, Xinji Wang, Peiru Li, Menyun Liu, Ruojin Yan, Chunmei Fan, Canlong Wang, Cunqi Ye, Hongwei Ouyang, Zi Yin, Xiao Chen, Weiliang Shen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2026-08-01
Serie:Bone Research
Accesso online:https://doi.org/10.1038/s41413-026-00574-w
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