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Automated H-Scoring in Muscle-Invasive Bladder Cancer IHC: An Internal Validation Study

<b>Background:</b> Immunohistochemistry (IHC) plays a central role in subtyping of muscle-invasive bladder cancer (MIBC), yet conventional semi-quantitative scoring lacks objectivity and scalability. Automated digital pathology offers potential solutions, but requires robust, marker-specific validat...

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Autori principali: Matthew Yap, Ioana-Maria Mihai, Maram Awadh A. Alanazi, Gheorghe-Emilian Olteanu, Alberto Contreras-Sanz, Peter Black, Gang Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2026-05-01
Serie:Diagnostics
Soggetti:
digital pathology
H-score
muscle-invasive bladder cancer
biomarker
QuPath
StarDist
Accesso online:https://www.mdpi.com/2075-4418/16/11/1673
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