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Senescent cells: New target for an old treatment?

Many genotoxic chemotherapies have debilitating side effects and induce cellular senescence in normal tissues. Senescent cells acquire a pro-inflammatory phenotype which contributes to local and systemic inflammation. Eliminating senescent cells reduce several short- and long-term effects of the dru...

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Bibliografiske detaljer
Hovedforfatter: Marco Demaria
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2017-05-01
Serier:Molecular & Cellular Oncology
Fag:
Online adgang:http://dx.doi.org/10.1080/23723556.2017.1299666
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