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Hematin- and Hemin-Induced Spherization and Hemolysis of Human Erythrocytes Are Independent of Extracellular Calcium Concentration

Pathologies such as malaria, hemorrhagic stroke, sickle cell disease, and thalassemia are characterized by the release of hemoglobin degradation products from damaged RBCs. Hematin (liganded with OH<sup>−</sup>) and hemin (liganded with Cl<sup>−</sup>)—are the oxidized forms of heme with toxic prope...

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Principais autores: Diana M. Mikhailova, Elisaveta Skverchinskaya, Julia Sudnitsyna, Kirill R. Butov, Ekaterina M. Koltsova, Igor V. Mindukshev, Stepan Gambaryan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2024-03-01
Series:Cells
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Acceso en liña:https://www.mdpi.com/2073-4409/13/6/554
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