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Enhanced glutamatergic and decreased GABAergic synaptic appositions to GnRH neurons on proestrus in the rat: modulatory effect of aging.

<h4>Background</h4>Previous work by our lab and others has implicated glutamate as a major excitatory signal to gonadotropin hormone releasing hormone (GnRH) neurons, with gamma amino butyric acid (GABA) serving as a potential major inhibitory signal. However, it is unknown whether GABAergic and/or...

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Autors principals: Mohammad Khan, Liesl De Sevilla, Virendra B Mahesh, Darrell W Brann
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2010-04-01
Col·lecció:PLoS ONE
Accés en línia:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0010172&type=printable
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