Construction of a pilocarpine-induced temporal lobe epilepsy model in mice based on severe seizure behavior

Objective To explore the approach to establish a temporal lobe epilepsy model via intraperitoneal pilocarpine injection in C57BL/6J mice, and to summarize behavioral indicators predicting successful modeling during the acute phase of epileptic seizures after pilocarpine administration, aiming to off...

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Principais autores:	Fangchao TONG, Yiying CAI, Yuanfang LI, Qiang WANG, Jing DING, Xin WANG
Format:	Artigo
Jezik:	Inglês
Izdano:	Shanghai Chinese Clinical Medicine Press Co., Ltd. 2024-10-01
Serija:	Zhongguo Linchuang Yixue
Teme:	mouse model temporal lobe epilepsy pilocarpine c57bl/6j mossy fiber sprouting neuronal death
Online dostop:	https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2024.20232043
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