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Immobilized fibrinogen activates human platelets through glycoprotein VI

Glycoprotein VI, a major platelet activation receptor for collagen and fibrin, is considered a particularly promising, safe antithrombotic target. In this study, we show that human glycoprotein VI signals upon platelet adhesion to fibrinogen. Full spreading of human platelets on fibrinogen was aboli...

Täydet tiedot

Tallennettuna:
Päätekijät: Pierre H Mangin, Marie-Blanche Onselaer, Nicolas Receveur, Nicolas Le Lay, Alexander T Hardy, Clare Wilson, Ximena Sanchez, Stéphane Loyau, Arnaud Dupuis, Amir K Babar, Jeanette LC Miller, Helen Philippou, Craig E Hughes, Andrew B Herr, Robert AS Ariëns, Diego Mezzano, Martine Jandrot-Perrus, Christian Gachet, Steve P. Watson
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ferrata Storti Foundation 2018-05-01
Sarja:Haematologica
Linkit:https://haematologica.org/article/view/8461
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