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Methyltransferase Setdb1 Promotes Osteoblast Proliferation by Epigenetically Silencing Macrod2 with the Assistance of Atf7ip

Bone loss caused by mechanical unloading is a threat to prolonged space flight and human health. Epigenetic modifications play a crucial role in varied biological processes, but the mechanism of histone modification on unloading-induced bone loss has rarely been studied. Here, we discovered for the...

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Principais autores: Lijun Zhang, Liqun Xu, Xiaoyan Zhang, Ke Wang, Yingjun Tan, Gaozhi Li, Yixuan Wang, Tong Xue, Quan Sun, Xinsheng Cao, Ge Zhang, Zebing Hu, Shu Zhang, Fei Shi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-08-01
Serier:Cells
Fag:
Setdb1
cell proliferation
mechanical unloading
bone loss
Online adgang:https://www.mdpi.com/2073-4409/11/16/2580
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