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Structural Basis for Capsid Recruitment and Coat Formation during HSV-1 Nuclear Egress

During herpesvirus infection, nascent viral capsids egress the nucleus into the cytoplasm by an unusual mechanism whereby capsids bud at the inner nuclear membrane. This process is mediated by the conserved heterodimeric nuclear egress complex (NEC), anchored to the inner nuclear membrane, that defo...

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Principais autores: Elizabeth Draganova, Jiayan Zhang, Hong Zhou, Ekaterina Heldwein
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-06-01
Serier:Proceedings
Fag:
herpes simplex virus type 1
herpesvirus
nuclear egress
nuclear egress complex
membrane budding
capsid budding
Online adgang:https://www.mdpi.com/2504-3900/50/1/101
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