Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia

IntroductionRadiation-induced thrombocytopenia (RIT) is a serious complication of cancer radiotherapy, for which therapeutic options are limited. This study investigates wedelolactone (WED), a metabolite of a botanical drug, as a potential treatment for RIT.MethodsIn vitro experiments were conducted...

Повний опис

Бібліографічні деталі

Автори:	Zhichao Li, Qinyao Li, Shuang Wu, Xinyue Mei, Xiao Qi, Sheng Liu, Gan Qiao, Hongping Shen, Jiesi Luo, Jing Zeng, Feihong Huang, Rong Li, Long Wang
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2025-04-01
Серія:	Frontiers in Pharmacology
Предмети:	wedelolactone thrombocytopenia oxidative phosphorylation megakaryocyte differentiation thrombopoiesis
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1508215/full
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!