Rapid generation of gene-targeted EPS-derived mouse models through tetraploid complementation
Abstract One major strategy to generate genetically modified mouse models is gene targeting in mouse embryonic stem (ES) cells, which is used to produce gene-targeted mice for wide applications in biomedicine. However, a major bottleneck in this approach is that the robustness of germline transmissi...
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| Principais autores: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018-06-01
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| Series: | Protein & Cell |
| Assuntos: | |
| Acceso en liña: | http://link.springer.com/article/10.1007/s13238-018-0556-1 |
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