α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb
Abstract Alpha-synuclein inclusions, the hallmarks of synucleinopathies, are suggested to spread along neuronal connections in a stereotypical pattern in the brains of patients. Ample evidence now supports that pathological forms of alpha-synuclein propagate in cell culture models and in vivo in a p...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2019-12-01
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| Seria: | Acta Neuropathologica Communications |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s40478-019-0859-3 |
| Etykiety: |
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