Improved overall survival in patients with high-grade serous ovarian cancer is associated with CD16a+ immunologic neighborhoods containing NK cells, T cells and macrophages

BackgroundFor patients with high grade serous carcinoma of the ovary (HGSC), survival rates have remained static for the last half century. Despite the presence of tumor mutations and infiltration of immune cells, existing immunotherapies have achieved little success against HGSC. These observations...

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Principais autores:	Sarah Nersesian, Riley J. Arseneau, Jorge P. Mejia, Stacey N. Lee, Lauren P. Westhaver, Nigel W. Griffiths, Stephanie R. Grantham, Liliane Meunier, Laudine Communal, Avik Mukherjee, Anne-Marie Mes-Masson, Thomas Arnason, Brad H. Nelson, Jeanette E. Boudreau
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-01-01
coleção:	Frontiers in Immunology
Assuntos:	natural killer (NK) cell ovarian cancer high grade serous cancer spatial biology CD16A
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1307873/full
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