ROP16 of <i>Toxoplasma gondii</i> Inhibits Innate Immunity by Triggering cGAS-STING Pathway Inactivity through the Polyubiquitination of STING

cGAS-STING signaling is a major pathway in inducing type Ⅰ IFN, which plays a crucial role in the defense against <i>T. gondii</i> infection. In contrast, <i>T. gondii</i> develops multiple strategies to counteract the host defense, causing serious diseases in a wide range of hosts. Here, we demonst...

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Principais autores:	Qi-Wang Jin, Ting Yu, Ming Pan, Yi-Min Fan, Si-Yang Huang
格式:	Artigo
语言:	Inglês
出版:	MDPI AG 2023-07-01
丛编:	Cells
主题:	<i>Toxoplasma gondii</i> ROP16 cGAS-STING pathway immune escape
在线阅读:	https://www.mdpi.com/2073-4409/12/14/1862
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