Broadly reactive monoclonal antibodies against beta-lactamases for immunodetection of bacterial resistance to antibiotics

Abstract With antibiotic resistance reaching alarming levels globally, rapid detection of resistance determinants is crucial for administering appropriate antimicrobial therapies. This study aimed to develop monoclonal antibodies (MAbs) against bacterial β-lactamases, which are key enzymes in antibi...

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Hlavní autoři:	Karolina Bielskė, Rasa Petraitytė-Burneikienė, Aliona Avižinienė, Justas Dapkūnas, Ieva Plikusienė, Silvija Juciutė, Miglė Stančiauskaitė, Aurelija Žvirblienė, Indrė Kučinskaitė-Kodzė
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-05-01
Edice:	Scientific Reports
Témata:	AmpC β-lactamases Class C β-lactamases β-lactamase detection Monoclonal antibodies Antibiotic resistance
On-line přístup:	https://doi.org/10.1038/s41598-025-04603-2
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