Variations in candidalysin amino acid sequence influence toxicity and host responses
ABSTRACT Candida albicans causes millions of mucosal infections in humans annually. Hyphal overgrowth on mucosal surfaces is frequently associated with tissue damage caused by candidalysin, a secreted peptide toxin that destabilizes the plasma membrane of host cells thereby promoting disease and imm...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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American Society for Microbiology
2024-08-01
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| Serie: | mBio |
| Soggetti: | |
| Accesso online: | https://journals.asm.org/doi/10.1128/mbio.03351-23 |
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