The DEAD-box RNA-binding protein DDX6 regulates parental RNA decay for cellular reprogramming to pluripotency.

Cellular transitions and differentiation processes require mRNAs supporting the new phenotype but also the clearance of existing mRNAs for the parental phenotype. Cellular reprogramming from fibroblasts to induced pluripotent stem cells (iPSCs) occurs at the early stage of mesenchymal epithelial tra...

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Autores principales:	Daisuke Kami, Tomoya Kitani, Akihiro Nakamura, Naoki Wakui, Rena Mizutani, Masahito Ohue, Fuyuki Kametani, Nobuyoshi Akimitsu, Satoshi Gojo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2018-01-01
Colección:	PLoS ONE
Acceso en línea:	https://doi.org/10.1371/journal.pone.0203708
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