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Structure-based design and characterization of novel fusion-inhibitory lipopeptides against SARS-CoV-2 and emerging variants

The ongoing pandemic of COVID-19, caused by SARS-CoV-2, has severely impacted the global public health and socio-economic stability, calling for effective vaccines and therapeutics. In this study, we continued our efforts to develop more efficient SARS-CoV-2 fusion inhibitors and achieved significan...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Danwei Yu, Yuanmei Zhu, Tao Jiao, Tong Wu, Xia Xiao, Bo Qin, Huihui Chong, Xiaobo Lei, Lili Ren, Sheng Cui, Jianwei Wang, Yuxian He
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2021-01-01
Schriftenreihe:Emerging Microbes and Infections
Schlagworte:
SARS-CoV-2
spike protein
membrane fusion
fusion inhibitor
lipopeptide
Online-Zugang:https://www.tandfonline.com/doi/10.1080/22221751.2021.1937329
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