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Tollip Negatively Regulates Vascular Smooth Muscle Cell–Mediated Neointima Formation by Suppressing Akt‐Dependent Signaling

Background Tollip, a well‐established endogenous modulator of Toll‐like receptor signaling, is involved in cardiovascular diseases. The aim of this study was to investigate the role of Tollip in neointima formation and its associated mechanisms. Methods and Results In this study, transient increases...

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Principais autores: Hong Zhi, Fu‐Han Gong, Wen‐Lin Cheng, Kongbo Zhu, Long Chen, Yuyu Yao, Xingzhou Ye, Xue‐Yong Zhu, Hongliang Li
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2018-06-01
Serier:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Fag:
differentiation
migration
neointima formation
proliferation
Tollip
vascular smooth muscle
Online adgang:https://www.ahajournals.org/doi/10.1161/JAHA.117.006851
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