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Identification and validation of cilia-associated molecular candidates deregulated in severe asthma

Abstract Background Asthma is characterised by a chronic inflammation and airway remodelling. The functionality of the asthma airway epithelium is altered, suggesting a central role in the pathophysiology. Cilia-associated abnormalities have been reported in the airway epithelium of asthmatic patien...

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Principais autores: Maëva A Devilliers, Lynda Saber Cherif, Audrey Brisebarre, Ruby Chouquet, Ludivine Bralet, Julien Ancel, Alexandre Vivien, Emilie Luczka-Majérus, Arnaud Bonnomet, Nathalie Lalun, Camille Taillé, Xavier Dubernard, Jean-Claude Mérol, Christophe Ruaux, Myriam Polette, Gaëtan Deslée, Jeanne-Marie Perotin, Valérian Dormoy
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-02-01
Colecção:Respiratory Research
Assuntos:
Asthma
Airways
Cilia
Epithelial cells
NEK6
PHLDB2
Acesso em linha:https://doi.org/10.1186/s12931-026-03548-y
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