Plasma Signaling Factors in Patients With Langerhans Cell Histiocytosis (LCH) Correlate With Relative Frequencies of LCH Cells and T Cells Within Lesions

Langerhans cell histiocytosis (LCH) lesions contain an inflammatory infiltrate of immune cells including myeloid-derived LCH cells. Cell-signaling proteins within the lesion environment suggest that LCH cells and T cells contribute majorly to the inflammation. Foxp3+ regulatory T cells (Tregs) are e...

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Autors principals:	Jenée Mitchell, Egle Kvedaraite, Tatiana von Bahr Greenwood, Magda Lourda, Jan-Inge Henter, Stuart P. Berzins, George Kannourakis
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-06-01
Col·lecció:	Frontiers in Pediatrics
Matèries:	Langerhans cell histiocytosis (LCH) LCH cells FoxP3+ regulatory T cells (Treg) mucosal associated invariant T cells (MAIT) active TGF-β cytokines
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fped.2022.872859/full
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