Targeting macrophage-mediated TGF-β/BMP signaling in ankylosing spondylitis: from inflammation to pathological bone formation
Ankylosing spondylitis (AS) is a chronic, immune-mediated disease characterized by inflammatory arthritis and pathological new bone formation, ultimately leading to spinal fusion and functional impairment. Despite effective suppression of inflammation by biologic agents targeting cytokines such as T...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2026-07-01
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| Collection: | Frontiers in Immunology |
| Sujets: | |
| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fimmu.2026.1788883/full |
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