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Thymosin-α1 binds with ACE and downregulates the expression of ACE2 in human respiratory epithelia

Background: Thymosin-α1 has been implicated into the treatment of novel respiratory virus Coronavirus Disease 2019 (COVID-19), but the underlying mechanisms are still disputable. Aim: Herein we aimed to reveal a previously unrecognized mechanism that thymosin-α1 prevents COVID-19 by binding with ang...

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Principais autores: Yu-Hang Zhang, Wen-Yu Wang, Xiao-Cong Pang, Zhi Wang, Cheng-Zhuo Wang, Hang Zhou, Bo Zheng, Yi-Min Cui
Formato: Artigo
Idioma:Inglês
Publicado em: IMR Press 2022-02-01
coleção:Frontiers in Bioscience-Landmark
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Acesso em linha:https://www.imrpress.com/journal/FBL/27/2/10.31083/j.fbl2702048
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