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A New Regioselective Synthesis of the Cysteine-Rich Peptide Linaclotide

Linaclotide is a 14-amino acid residue peptide approved by the FDA for the treatment of irritable bowel syndrome with constipation (IBS-C), which activates guanylate cyclase C to accelerate intestinal transit. Here we show a new method for the synthesis of linaclotide through the completely selectiv...

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Bibliografiset tiedot
Päätekijät: Zhonghao Qiu, Xiandong Dai, Chongxu Fan, Ying Cao, Zirui Lv, Xingyong Liang, Fanhua Meng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2023-01-01
Sarja:Molecules
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Linkit:https://www.mdpi.com/1420-3049/28/3/1007
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