MiR-21 regulates skeletal muscle atrophy and fibrosis by targeting TGF-beta/SMAD7-SMAD2/3 signaling pathway

Long-term denervation-induced atrophy and fibrosis of skeletal muscle due to denervation leads to poor recovery of muscle function. Studies have shown that the transforming growth factor-β1 (TGF-β1)-Smad signaling pathway plays a central role in muscle atrophy and fibrosis. Recent studies demonstrat...

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Hlavní autoři:	Xianmin Song, Fei Liu, Mengjie Chen, Minhui Zhu, Hongliang Zheng, Wei Wang, Donghui Chen, Meng Li, Shicai Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-06-01
Edice:	Heliyon
Témata:	Skeletal muscle Atrophic fibrosis miR-21 SMAD7 SMAD2/3 Nuclear translocation
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2405844024090935
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