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Predictors of osteoclast activity in patients with sickle cell disease

Background Bone changes are common in sickle cell disease, but the pathogenesis is not fully understood. Tartrate-resistant acid phosphatase (TRACP) type 5b is produced by bone-resorbing osteoclasts. In other forms of hemolytic anemia, increased iron stores are associated with osteoporosis. We hypot...

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Главные авторы: Mehdi Nouraie, Kevin Cheng, Xiaomei Niu, Evadne Moore-King, Margaret F. Fadojutimi-Akinsi, Caterina P. Minniti, Craig Sable, Sohail Rana, Niti Dham, Andrew Campbell, Gregory Ensing, Gregory J. Kato, Mark T. Gladwin, Oswaldo L. Castro, Victor R. Gordeuk
Формат: Artigo
Язык:Inglês
Опубликовано: Ferrata Storti Foundation 2011-08-01
Серии:Haematologica
Online-ссылка:https://haematologica.org/article/view/6034
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