The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain.
Backbone hydrogen bonds are important for the structure and stability of proteins. However, since conventional site-directed mutagenesis cannot be applied to perturb the backbone, the contribution of these hydrogen bonds in protein folding and stability has been assessed only for a very limited set...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Public Library of Science (PLoS)
2014-01-01
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| Schriftenreihe: | PLoS ONE |
| Online-Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24748272/pdf/?tool=EBI |
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