BAMSE: Bayesian model selection for tumor phylogeny inference among multiple samples

Abstract Background Intra-tumor heterogeneity is known to contribute to cancer complexity and drug resistance. Understanding the number of distinct subclones and the evolutionary relationships between them is scientifically and clinically very important and still a challenging problem. Results In th...

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Bibliografski detalji

Glavni autori:	Hosein Toosi, Ali Moeini, Iman Hajirasouliha
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2019-06-01
Serija:	BMC Bioinformatics
Teme:	Bayesian model selection DNA sequencing Tumor phylogeny Computational cancer genomics Next generation sequencing Tumor heterogeneity
Online pristup:	http://link.springer.com/article/10.1186/s12859-019-2824-3
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