Sonic Hedgehog and WNT Signaling Regulate a Positive Feedback Loop Between Intestinal Epithelial and Stromal Cells to Promote Epithelial RegenerationSummary

Background and aims: Active intestinal stem cells are prone to injury by ionizing radiation. We previously showed that upon radiation-induced injury, normally quiescent reserve intestinal stem cells (rISCs) (marked by BMI1) are activated by Musashi-1 (MSI1) and exit from the quiescent state to regen...

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Κύριοι συγγραφείς:	Emilia J. Orzechowska-Licari, Agnieszka B. Bialkowska, Vincent W. Yang
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2023-01-01
Σειρά:	Cellular and Molecular Gastroenterology and Hepatology
Θέματα:	Sonic Hedgehog WNT Signaling MSI1 GLI1 Intestinal Epithelium Regeneration
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2352345X23001315
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